Correction: Increased Blood-Reelin-Levels in First Episode Schizophrenia
نویسندگان
چکیده
Dr. Carola Haas should be listed as the second author, and her affiliation is: Department of Neurosurgery, Exp. Epilepsy Research, Albert-Ludwigs-University, Breisacher Strasse 64, 79106 Freiburg, Germany. The contributions of this author are as follows: Analyzed the data, contributed reagents/materials/analysis tools. The correct citation is: Hornig T, Haas C, Sturm L, Fiebich B, Tebartz van Elst L (2015) Increased Blood-Reelin-Levels in First Episode Schizophrenia. PLoS ONE 10(8): e0134671. doi:10.1371/journal.pone.0134671
منابع مشابه
Increased Blood-Reelin-Levels in First Episode Schizophrenia
BACKGROUND Reelin is an extracellular glycoprotein involved in several functions of brain development, synaptogenesis and dendritic proliferation. Numerous studies found perturbation in the reelin system and altered serum reelin levels in neuropsychiatric patients using the western blot procedure. In the international literature, this is the first study that made use of an enzyme-linked immunos...
متن کاملIncreased serum dehydroepiandrosterone sulfate in the first episode but not in subsequent episodes in male patients with schizophrenia
BACKGROUND Many studies have investigated the relationship between blood levels of dehydroepiandrosterone (DHEA) and its sulfate ester (DHEA-S), cortisol, progesterone, and testosterone and the onset, prognosis, symptom severity, and treatment response of schizophrenia. In the present study, we assessed potential differences in blood levels of neurosteroids between drug-naïve first-episode pati...
متن کاملReelin Secreted by GABAergic Neurons Regulates Glutamate Receptor Homeostasis
BACKGROUND Reelin is a large secreted protein of the extracellular matrix that has been proposed to participate to the etiology of schizophrenia. During development, reelin is crucial for the correct cytoarchitecture of laminated brain structures and is produced by a subset of neurons named Cajal-Retzius. After birth, most of these cells degenerate and reelin expression persists in postnatal an...
متن کاملAre Uric Acid Levels Different from Healthy Subjects in Bipolar Affective Disorder and Schizophrenia?: Relationship Between Clinical Improvement and Episode Severity in Male Patients.
INTRODUCTION Purinergic system dysfunction has been shown both in patients with bipolar disorder (BD) and those with schizophrenia. The aim of this study was to evaluate whether uric acid levels in male BD patients with manic episode and schizophrenia patients with psychotic relapse differ from healthy male subjects. Secondly to assess whether uric acid levels in both patient groups correlate w...
متن کاملReelin promoter hypermethylation in schizophrenia.
Reelin mRNA and protein levels are reduced by approximately 50% in various cortical structures of postmortem brain from patients diagnosed with schizophrenia or bipolar illness with psychosis. In addition, the mRNA encoding the methylating enzyme, DNA methyltransferase 1, is up-regulated in the same neurons that coexpress reelin and glutamic acid decarboxylase 67. We have analyzed the extent an...
متن کامل